This is common with ink cartridges that have attached print heads (such as HP, Lexmark or Dell). Cartridges are typically kept flat or upside down for weeks or months before being used. As a result, the ink will settle at the other end of the cartridge and will be unable to directly feed the print head. The easiest remedy for this is to open the box and stand the cartridge upside down for a few minutes before using. Next, get a damp paper towel, fold it into quarters and the set cartridge print head down onto it, holding it there for three minutes. This will help to prime the print head and pull the ink out. Finally, install the cartridge into your printer and print a few test pages.